CALL FOR PAPERS Cardiovascular Responses to Environmental Stress Perinatal hypoxia increases susceptibility to high-altitude polycythemia and attendant pulmonary vascular dysfunction
نویسندگان
چکیده
Colleen Glyde Julian, Marcelino Gonzales, Armando Rodriguez, Diva Bellido, Carlos Salinas Salmon, Anne Ladenburger, Lindsay Reardon, Enrique Vargas, and Lorna G. Moore Department of Medicine, University of Colorado School of Medicine, Aurora, Colorado; Bolivian Institute of High Altitude Biology, La Paz, Bolivia; Department of Obstetrics and Gynecology, University of Utah, Salt Lake City, Utah; Department of Emergency Medicine, Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire; and Department of Obstetrics and Gynecology, University of Colorado School of Medicine, Aurora, Colorado
منابع مشابه
Perinatal hypoxia increases susceptibility to high-altitude polycythemia and attendant pulmonary vascular dysfunction.
Perinatal exposures exert a profound influence on physiological function, including developmental processes vital for efficient pulmonary gas transfer throughout the lifespan. We extend the concept of developmental programming to chronic mountain sickness (CMS), a debilitating syndrome marked by polycythemia, ventilatory impairment, and pulmonary hypertension that affects ∼10% of male high-alti...
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Introduction: Chronic mountain sickness (CMS) represents a syndrome of secondary polycythemia along with thrombocytopenia, altered hemorheology, pulmonary and systemic hypertension, and congestive heart failure, occurring due to hypobaric hypoxia-anoxia-induced erythropoiesis reported in both native mountain residents and new climbers after prolonged stays at high and extreme a...
متن کاملEffect of altitude and cobalt polycythemia, hypoxia, and cortisone on susceptibility of rats to endocarditis.
Rats with polycythemia induced by exposures to simulated high altitudes developed a significantly higher incidence of endocarditis following intravenous bacterial injections than rats with cobalt polycythemia or ground level controls. No increase occurred in altitude rats when polycythemia was prevented by repeated bleedings. These findings suggest that both polycythemia and hypoxia are necessa...
متن کاملEftect ot Altitude and Cobalt Polycythemia, Hypoxia, and Cortisone on Susceptibility of Rats to Endocarditis
Rats with polycythemia induced by exposures to simulated high altitudes developed a significantly higher incidence of endocarditis following intravenous bacterial injections than rats with cobalt polycythemia or ground level controls. No increase occurred in altitude rats when polycythemia was prevented by repeated bleedings. These findings suggest that both polycythemia and hypoxia are necessa...
متن کاملEftect ot Altitude and Cobalt Polycythemia, Hypoxia, and Cortisone on Susceptibility of Rats to Endocarditis
Rats with polycythemia induced by exposures to simulated high altitudes developed a significantly higher incidence of endocarditis following intravenous bacterial injections than rats with cobalt polycythemia or ground level controls. No increase occurred in altitude rats when polycythemia was prevented by repeated bleedings. These findings suggest that both polycythemia and hypoxia are necessa...
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